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Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia

Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 416-420 doi: 10.1007/s11684-012-0224-4

Abstract:

Acute lymphoblastic leukemia includes T-cell acute lymphoblastic leukemia (T-ALL) and B-cell acutephenotype that resembles early T-cell precursor, which confers a much poorer prognosis than any otherform of T-ALL.This novel subtype of T-ALL was called early T-cell precursor acute lymphoblastic leukemia (ETP-ALL).Our findings demonstrate that early T-cell precursor leukemia is a very high-risk subtype of acute lymphoblastic

Keywords： acute lymphoblastic leukemia     early T precursor     prognosis    

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A reignited debate over the cell(s) of origin for glioblastoma and its clinical implications

Xiaolin Fan, Yanzhen Xiong, Yuan Wang

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 531-539 doi: 10.1007/s11684-019-0700-1

Abstract: are primary GBMs that are full-blown at diagnosis without evidences of a pre-existing less-malignant precursorNeural stem cells and oligodendrocyte precursor cells are the two major candidates for the cell(s) ofprogress and debate in the field, explore the clinical implications, and propose future directions toward early

Keywords： glioblastoma     cell(s) of origin     neural stem cells     oligodendrocyte precursor cells     subventricular zone     early diagnosis    

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Orthopedic management in the polytrauma patient

Halvorson, Holly T-P. Pilson, Eben A. Carroll, Zhongyu John Li

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 234-242 doi: 10.1007/s11684-012-0218-2

Abstract: Early recommendations for non-operative treatment have evolved into early total care (ETC) and damage

Keywords： damage control orthopedics     early total care     polytrauma    

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Tracking of safety hazards and real-time-prediction model of safety risks on construction sites

Wu Weiwei,Patrick T. I. LAM,Li Qiming,Michael C. H. YAM,David A. S. CHEW

Strategic Study of CAE 2010, Volume 12, Issue 3,   Pages 68-72

Abstract: risks, while serving as a foundation for further study by drawing researchers' attention to the precursor

Keywords： construction sites     safety risks     real-time prediction     precursor signals     signal detection theory    

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The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease

Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 437-442 doi: 10.1007/s11684-009-0074-x

Abstract: Natriuretic peptide precursor A (NPPA) is synthesized, stored, and released by atrial myocytes.

Keywords： natriuretic peptide precursor A     coronary heart disease     gene polymorphism     allelic discrimination     polymorphism    

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Carbon-coated lithium titanate: effect of carbon precursor addition processes on the electrochemical

Shilei Ding, Zelong Jiang, Jing Gu, Hongliang Zhang, Jiajia Cai, Dongdong Wang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 1,   Pages 148-155 doi: 10.1007/s11705-020-2022-x

Abstract: composites were synthesized using the ball-milling-assisted calcination method with different carbon precursor

Keywords： lithium titanate     carbon-coated     carbon precursor     synthetic process    

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Effects of exercise therapy on bone mineral density in early postmenopausal women: a controlled trial

Shilin DENG MD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 323-329 doi: 10.1007/s11684-009-0061-2

Abstract: Further, the exact dose-response relationship of exercise and bone mass in early postmenopause is not

Keywords： early postmenopausal women     bone mineral density     exercise     effects    

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RESEARCH AND APPLICATION OF CROP PEST MONITORING AND EARLY WARNING TECHNOLOGY IN CHINA

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1,   Pages 19-36 doi: 10.15302/J-FASE-2021411

Abstract: Nevertheless, the use of science and technology in monitoring and early warning of major crop pests providesThis review summarizes the most fundamental information on pest monitoring and early warning in Chinaapplication, Chinese laws and regulations related to plant protection, and the National Monitoring and Early

Keywords： China / law / early warning system and national crop pest monitoring / pest management / regulation and    

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Expression of inducible nitric oxide synthase in trophoblasts and deciduas in early medical abortion

Geqing XIA, Chaoying WU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 216-219 doi: 10.1007/s11684-009-0028-3

Abstract: was to investigate the expression of inducible nitric oxide synthase in trophoblasts and deciduas in earlyrelationship of medical abortion through mifepristone and inducible nitric oxide synthase (iNOS) in early

Keywords： mifepristone     inducible nitric oxide synthase     early pregnancy     placental immunity    

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Particle formation of hydroxyapatite precursor containing two components in a spray pyrolysis process

W. Widiyastuti, Adhi Setiawan, Sugeng Winardi, Tantular Nurtono, Heru Setyawan

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 1,   Pages 104-113 doi: 10.1007/s11705-014-1406-1

Abstract: The particle formation mechanism of hydroxyapatite precursor containing two components, Ca(OOCCH ) anddroplets, a second evaporation due to crust formation, the decomposition reaction of each component of the precursor, and a solid-state reaction that included the kinetic parameters of the precursor regarding its twoThe rate of evaporation and the reacted fraction of the precursor both increased with temperature.were also suitable for predicting the average size of particles that contain two components in the precursor

Keywords： droplet     hydroxyapatite particle     CFD     tubular furnace     spray pyrolysis    

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Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia

Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 347-371 doi: 10.1007/s11684-020-0821-6

Abstract: B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by genetic alterations withinhibitors (e.g., imatinib), immunomodulators, monoclonal antibodies, and chimeric antigen receptor T-cell(CAR-T) therapy, are transforming the clinical practice from chemotherapy drugs to personalized medicine

Keywords： BCP-ALL     subtypes     translocation     aneuploidy     sequence mutations    

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Role of chemerin/CMKLR1 in the maintenance of early pregnancy

Xuezhou Yang, Junning Yao, Qipeng Wei, Jinhai Ye, Xiaofang Yin, Xiaozhen Quan, Yanli Lan, Hui Xing

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 525-532 doi: 10.1007/s11684-017-0577-9

Abstract: explore the effects of chemerin and its receptor chemokine-like receptor 1 (CMKLR1) on the maintenance of earlyThe expression levels of chemerin and CMKLR1 in the decidua tissues of 20 early normal pregnant womenand 20 early spontaneous abortion women were examined by Western blot and real-time polymerase chainWe found that the expression level of chemerin in women who had experienced early spontaneous abortionwas lower than in those who had experienced normal early pregnancy (P<0.01); conversely, CMKLR1

Keywords： chemerin     CMKLR1     early abortion    

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Weak characteristic information extraction from early fault of wind turbine generator gearbox

Xiaoli XU, Xiuli LIU

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 3,   Pages 357-366 doi: 10.1007/s11465-017-0423-4

Abstract:

Given the weak early degradation characteristic information during early fault evolution in gearboxmethod can significantly weaken signal noise, effectively extract the weak characteristic information of earlyfault, and facilitate the early fault warning and dynamic predictive maintenance.

Keywords： µ-singular value decomposition     local mean decomposition     weak characteristic information extraction     early    

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Early-onset diabetes: an epidemic in China

Jiemin Pan, Weiping Jia

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 624-633 doi: 10.1007/s11684-018-0669-1

Abstract:

Although type 2 diabetes is a disease often associated with aging, the global prevalence of early-onsetMany studies have found that individuals with early-onset type 2 diabetes were at higher risk of developingIndividuals with early-onset diabetes are usually unwilling to visit hospital and have more confidenceScreening for T2DM is imminent for young adults with a family history of diabetes, obesity, markers ofMore data are definitely required to establish a reasonable risk model to screen for early-onset diabetes

Keywords： diabetes     early-onset     diabetes complications    

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Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 157-175 doi: 10.1007/s11684-021-0884-z

Abstract: Therefore, early diagnosis of cancer is indispensable in the timely prevention and effective treatmentExosome has recently become an attractive cancer biomarker in noninvasive early diagnosis because of, high sensitivity, and remarkable specificity, suggesting promising biomedical applications in the earlyregarding the assay of exosomes were summarized, and the superiorities of exosomes as markers for the earlyMoreover, the recent challenges and further opportunities of developing effective biosensors for the early

Keywords： biosensor     exosome     cancer diagnosis    

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Title Author Date Type Operation

Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia

Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen

Journal Article

A reignited debate over the cell(s) of origin for glioblastoma and its clinical implications

Xiaolin Fan, Yanzhen Xiong, Yuan Wang

Journal Article

Orthopedic management in the polytrauma patient

Halvorson, Holly T-P. Pilson, Eben A. Carroll, Zhongyu John Li

Journal Article

Tracking of safety hazards and real-time-prediction model of safety risks on construction sites

Wu Weiwei,Patrick T. I. LAM,Li Qiming,Michael C. H. YAM,David A. S. CHEW

Journal Article

The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease

Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,

Journal Article

Carbon-coated lithium titanate: effect of carbon precursor addition processes on the electrochemical

Shilei Ding, Zelong Jiang, Jing Gu, Hongliang Zhang, Jiajia Cai, Dongdong Wang

Journal Article

Effects of exercise therapy on bone mineral density in early postmenopausal women: a controlled trial

Shilin DENG MD ,

Journal Article

RESEARCH AND APPLICATION OF CROP PEST MONITORING AND EARLY WARNING TECHNOLOGY IN CHINA

Journal Article

Expression of inducible nitric oxide synthase in trophoblasts and deciduas in early medical abortion

Geqing XIA, Chaoying WU

Journal Article

Particle formation of hydroxyapatite precursor containing two components in a spray pyrolysis process

W. Widiyastuti, Adhi Setiawan, Sugeng Winardi, Tantular Nurtono, Heru Setyawan

Journal Article

Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia

Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen

Journal Article

Role of chemerin/CMKLR1 in the maintenance of early pregnancy

Xuezhou Yang, Junning Yao, Qipeng Wei, Jinhai Ye, Xiaofang Yin, Xiaozhen Quan, Yanli Lan, Hui Xing

Journal Article

Weak characteristic information extraction from early fault of wind turbine generator gearbox

Xiaoli XU, Xiuli LIU

Journal Article

Early-onset diabetes: an epidemic in China

Jiemin Pan, Weiping Jia

Journal Article

Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Journal Article